Enzymes Relevant to Kojic Acid Biosynthesis in Aspergillus flavus
نویسندگان
چکیده
منابع مشابه
Cyclopiazonic Acid Biosynthesis of Aspergillus flavus and Aspergillus oryzae
Cyclopiazonic acid (CPA) is an indole-tetramic acid neurotoxin produced by some of the same strains of A. flavus that produce aflatoxins and by some Aspergillus oryzae strains. Despite its discovery 40 years ago, few reviews of its toxicity and biosynthesis have been reported. This review examines what is currently known about the toxicity of CPA to animals and humans, both by itself or in comb...
متن کاملThe Biosynthesis of Kojic Acid
Barker, S. B., Kiely, C. E., Dirks, H. B., Klitgaard, H. M., Wang, S. C. & Wawzonek, S. (1950). J. Phlarmacol. 99, 202. Barnes, J. H., Elks, J., Stephens, F. F. & Waller, G. J. (1953). J. chem. Soc. p. 764. Cortell, R. E. (1949). J. clin. Endocrin. 9, 955. Datta, R. L. & Prosad, N. (1917). J. Amer. chem. Soc. 39, 443. Frieden, E. & Winzler, R. J. (1949). J. biol. Chem. 179, 423. Kalb, L., Schwe...
متن کاملExpression of aflR, veA and laeA as regulators of aflatoxins and cyclopiazonic acid biosynthesis pathway in Aspergillus flavus
In this study, the production of aflatoxin B1 (AFB1) and cyclopiazonic acid (CPA) was investigated in toxigenic and non-toxigenic Aspergillus flavus with respect to expression of aflR, veA and laeA genes that are involved to toxins production. A. flavus strains were cultured in YES broth at 28 °C for 4 days and the presence of (AFB1) and (CPA) was confirmed and measured by TLC and HPLC. The exp...
متن کاملHow Peroxisomes Affect Aflatoxin Biosynthesis in Aspergillus Flavus
In filamentous fungi, peroxisomes are crucial for the primary metabolism and play a pivotal role in the formation of some secondary metabolites. Further, peroxisomes are important site for fatty acids β-oxidation, the formation of reactive oxygen species and for their scavenging through a complex of antioxidant activities. Oxidative stress is involved in different metabolic events in all organi...
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ژورنال
عنوان ژورنال: Microbiology
سال: 1981
ISSN: 1350-0872,1465-2080
DOI: 10.1099/00221287-127-1-131